Tantargy

Data

Official data in SubjectManager for the following academic year: 2024-2025

Course director

Number of hours/semester

Lectures: 28 hours

Practices: 0 hours

Seminars: 0 hours

Total of: 28 hours

Subject data

  • Code of subject: OPF-CHS-T
  • 2 Credit
  • Pharmacy
  • Optional module
  • autumn
Prerequisites:

OPA-ALK_23-T finished

Course headcount limitations

min. 5 people – max. 15 people

Topic

Objectives and scope: Chemical sensors are important tools for everyday use. Using them concentration of different species can be given – real time- in complex matrices, such as blood, air or wastewaters. Students taking the course will learn the different kind of sensors. We demonstrate their structures, working principles and the selective recognition mechanisms. Depending on the field of application, the advantages and disadvantages of their use will be also discussed.  Sensors used in medicine, medical diagnostics and process control will be also discussed in details.

Lectures

  • 1.

    Sensors, physical and chemical sensors

    - Kovács Barna Szilárd
  • 2.

    Application field of chemical sensors, history of their development

    - Kovács Barna Szilárd
  • 3.

    Major analytical characteristics of their performance: stability, selectivity

    - Kovács Barna Szilárd
  • 4.

    Sensitivity, lower limit of detection, response times

    - Kovács Barna Szilárd
  • 5.

    Sensors for the measurements of mechanical deformations and electric changes

    - Kovács Barna Szilárd
  • 6.

    Transducers. Electrochemical sensors

    - Kovács Barna Szilárd
  • 7.

    Ion selective electrodes

    - Kovács Barna Szilárd
  • 8.

    Chemically modified amperometric electrodes

    - Kovács Barna Szilárd
  • 9.

    Selective gas sensors

    - Kovács Barna Szilárd
  • 10.

    Capacitance based sensors, humidity sensors, gas sensors

    - Kovács Barna Szilárd
  • 11.

    Group work

    - Kovács Barna Szilárd
  • 12.

    Group work

    - Kovács Barna Szilárd
  • 13.

    Sensors detecting mass changes: Quartz crystal micro balance (QCM) and surface acoustic wave sensors (SAW), surface plasmon resonance detection based sensors (SPR)

    - Kovács Barna Szilárd
  • 14.

    Optical chemical sensors, principle of operation

    - Kovács Barna Szilárd
  • 15.

    Conventional optodes, wave guides, fiber optics

    - Kovács Barna Szilárd
  • 16.

    Fluorescence based sensors

    - Kovács Barna Szilárd
  • 17.

    Attenuated total internal reflection (ATIR) based optodes

    - Kovács Barna Szilárd
  • 18.

    Semiconductor based sensors, solid electrolyte based gas sensors

    - Kovács Barna Szilárd
  • 19.

    Chemically sensitized FETs

    - Kovács Barna Szilárd
  • 20.

    Group work

    - Kovács Barna Szilárd
  • 21.

    Group work

    - Kovács Barna Szilárd
  • 22.

    Biosensors I: Enzymes based biocatalytic layers

    - Kovács Barna Szilárd
  • 23.

    Bacteria containing biocatalytic layers

    - Kovács Barna Szilárd
  • 24.

    Biosensors II: Receptor based sensors, and immuno-complex based sensing

    - Kovács Barna Szilárd
  • 25.

    RNA/DNA fragment based sensors, aptamer sensing, MIPs

    - Kovács Barna Szilárd
  • 26.

    Group work

    - Kovács Barna Szilárd
  • 27.

    Group work

    - Kovács Barna Szilárd
  • 28.

    Summary, test

    - Kovács Barna Szilárd

Practices

Seminars

Reading material

Obligatory literature

R.W. Cattrall: Chemical Sensors, Oxford Science, 1997

B.R. Eggins: Biosensors: an Introduction, Wiley, 1996

Literature developed by the Department

Notes

Recommended literature

J. Janata: Principles of Chemical sensors, Plenum Press, 1989

T.E. Edmonds: Chemical sensors, Blackie, 1988

Conditions for acceptance of the semester

Participating in the project groupwork, grade of the written test

Mid-term exams

Oral, during the project groupwork

Making up for missed classes

By arrangement with the lecturer

Exam topics/questions

-

Examiners

  • Kovács Barna Szilárd

Instructor / tutor of practices and seminars