Data
Official data in SubjectManager for the following academic year: 2024-2025
Course director
Pongrácz Judit Erzsébet
professor,
Faculty of Health Sciences - Institute of Health Science, Department of Public Health
Number of hours/semester
Lectures: 14 hours
Practices: 28 hours
Seminars: 14 hours
Total of: 56 hours
Subject data
- Code of subject: OTV-GGM2-T
- 7 Credit
- Biotechnology BSc
- Specialised Core Module module
- spring
Prerequisites:
OTV-BIC2-T finished , OTV-GGM1-T finished
Course headcount limitations
min. 5 people – max. 50 people
Topic
The subject expands on the knowledge which was accumulated in the previous semester. Gene mutation, DNA repair mechanisms and transposition, regulation of gene expression, transcriptional and post-transcriptional regulation will be discussed. Finally, epigenetic regulation of gene expression and its consequences will be the final topic.
Lectures
- 4. Induced mutations induced by chemicals and radiation II. - Pongrácz Judit Erzsébet
- 3. Induced mutations induced by chemicals and radiation I. - Pongrácz Judit Erzsébet
- 2. Replication errors and Base modifications - Pongrácz Judit Erzsébet
- 1. Gene mutations - Pongrácz Judit Erzsébet
- 5. Mutations in the background of human diseases I. - Pongrácz Judit Erzsébet
- 6. Mutations in the background of human diseases II. - Pongrácz Judit Erzsébet
- 7. Transposable elements - Pongrácz Judit Erzsébet
- 8. Regulation of gene expression in bacteria - Pongrácz Judit Erzsébet
- 9. Regulation of gene expression in Eukaryotes - Pongrácz Judit Erzsébet
- 10. Transcriptional regulation in Eukaryotes - Pongrácz Judit Erzsébet
- 11. The epigenome - Pongrácz Judit Erzsébet
- 12. Regulation of the epigenome - Pongrácz Judit Erzsébet
- 13. Epigenetics and diseases - Pongrácz Judit Erzsébet
- 14. Epigenetic traits - Pongrácz Judit Erzsébet
Practices
- 9. The effect of UV irradiation on gene expression - Ádám Zoltán Mihály
- 8. The effect of UV irradiation on cellular morphology and function - Garai Kitti
...
- 7. The effect of UV irradiation on cellular morphology and function - Garai Kitti
- 6. The effect of UV irradiation on cellular morphology and function - Garai Kitti
- 5. The effect of UV irradiation on cellular morphology and function - Garai Kitti
- 4. Sequence alignments - Garai Kitti
...
- 3. Sequence alignments - Garai Kitti
- 2. Sequence alignments - Garai Kitti
- 1. Sequence alignments - Garai Kitti
- 10. The effect of UV irradiation on gene expression - Ádám Zoltán Mihály
...
- 11. The effect of UV irradiation on gene expression - Ádám Zoltán Mihály
- 12. The effect of UV irradiation on gene expression - Ádám Zoltán Mihály
- 13. BLASTS - bioinformatics - Ádám Zoltán Mihály
- 14. BLASTS - bioinformatics - Ádám Zoltán Mihály
- 15. BLASTS - bioinformatics - Garai Kitti
- 16. BLASTS - bioinformatics - Garai Kitti
- 17. Designing disease models - Chromosomal modification - Downsyndrome mouse model - Garai Kitti
...
- 18. Designing disease models - Chromosomal modification - Downsyndrome mouse model - Garai Kitti
- 19. Designing disease models - Chromosomal modification - Downsyndrome mouse model - Garai Kitti
- 20. Designing disease models - Chromosomal modification - Downsyndrome mouse model - Garai Kitti
- 21. Designing disease models - transposons - Garai Kitti
- 22. Designing disease models - transposons - Garai Kitti
- 23. Designing disease models - transposons - Ádám Zoltán Mihály
- 24. Designing disease models - transposons - Ádám Zoltán Mihály
- 25. Swiss prot - protein sequences in disease analysis - Ádám Zoltán Mihály
...
- 26. Swiss prot - protein sequences in disease analysis - Ádám Zoltán Mihály
- 27. Swiss prot - protein sequences in disease analysis - Ádám Zoltán Mihály
- 28. Swiss prot - protein sequences in disease analysis - Ádám Zoltán Mihály
Seminars
- 3. Induced mutations induced by chemicals - Garai Kitti
- 2. Replication errors and Base modifications - Garai Kitti
- 1. Replication errors and Base modifications - Garai Kitti
- 4. Induced mutations induced by radiation - Garai Kitti
- 5. Mutations in the background of human diseases case study I. - Garai Kitti
- 6. Mutations in the background of human diseases case study II. - Garai Kitti
- 7. Mutations in the background of human diseases case study III. - Garai Kitti
- 8. Comparison of gene expression regulation in bacteria and humans I. - Garai Kitti
- 9. Comparison of gene expression regulation in bacteria and humans II. - Ádám Zoltán Mihály
- 10. Comparison of gene expression regulation in bacteria and humans III. - Ádám Zoltán Mihály
- 11. Comparison of gene expression regulation in bacteria and humans IV. - Ádám Zoltán Mihály
- 12. Epigenetics in the background of human diseases case study I. - Ádám Zoltán Mihály
- 13. Epigenetics in the background of human diseases case study II. - Ádám Zoltán Mihály
- 14. Epigenetics in the background of human diseases case study III. - Ádám Zoltán Mihály
Reading material
Obligatory literature
Literature developed by the Department
Own ppt, interactive teaching material
Notes
Recommended literature
Klug et al: Concepts of Genetics 12th Edition
Pierce: Genetics - A Conceptual Approach 7th Edition (2020)
Conditions for acceptance of the semester
75% attendance to lectures and 85% to seminars and practices
Mid-term exams
One midterm test, that can be repeated two more times if necessary.
Making up for missed classes
None
Exam topics/questions
Teams, Neptun, Departmental website
Examiners
- Garai Kitti
- Pongrácz Judit Erzsébet
Instructor / tutor of practices and seminars
- Ádám Zoltán Mihály
- Draskóczi Lilla Gréta
- Garai Kitti