Tantargy

Data

Official data in SubjectManager for the following academic year: 2024-2025

Course director

Number of hours/semester

Lectures: 14 hours

Practices: 28 hours

Seminars: 14 hours

Total of: 56 hours

Subject data

  • Code of subject: OTV-GGM2-T
  • 7 Credit
  • Biotechnology BSc
  • Specialised Core Module module
  • spring
Prerequisites:

OTV-BIC2-T finished , OTV-GGM1-T finished

Course headcount limitations

min. 5 people – max. 50 people

Topic

The subject expands on the knowledge which was accumulated in the previous semester. Gene mutation, DNA repair mechanisms and transposition, regulation of gene expression, transcriptional and post-transcriptional regulation will be discussed. Finally, epigenetic regulation of gene expression and its consequences will be the final topic.

Lectures

  • 4. Induced mutations induced by chemicals and radiation II. - Pongrácz Judit Erzsébet
  • 3. Induced mutations induced by chemicals and radiation I. - Pongrácz Judit Erzsébet
  • 2. Replication errors and Base modifications - Pongrácz Judit Erzsébet
  • 1. Gene mutations - Pongrácz Judit Erzsébet
  • 5. Mutations in the background of human diseases I. - Pongrácz Judit Erzsébet
  • 6. Mutations in the background of human diseases II. - Pongrácz Judit Erzsébet
  • 7. Transposable elements - Pongrácz Judit Erzsébet
  • 8. Regulation of gene expression in bacteria - Pongrácz Judit Erzsébet
  • 9. Regulation of gene expression in Eukaryotes - Pongrácz Judit Erzsébet
  • 10. Transcriptional regulation in Eukaryotes - Pongrácz Judit Erzsébet
  • 11. The epigenome - Pongrácz Judit Erzsébet
  • 12. Regulation of the epigenome - Pongrácz Judit Erzsébet
  • 13. Epigenetics and diseases - Pongrácz Judit Erzsébet
  • 14. Epigenetic traits - Pongrácz Judit Erzsébet

Practices

  • 9. The effect of UV irradiation on gene expression - Ádám Zoltán Mihály
  • 8. The effect of UV irradiation on cellular morphology and function - Garai Kitti
  • ...
  • 7. The effect of UV irradiation on cellular morphology and function - Garai Kitti
  • 6. The effect of UV irradiation on cellular morphology and function - Garai Kitti
  • 5. The effect of UV irradiation on cellular morphology and function - Garai Kitti
  • 4. Sequence alignments - Garai Kitti
  • ...
  • 3. Sequence alignments - Garai Kitti
  • 2. Sequence alignments - Garai Kitti
  • 1. Sequence alignments - Garai Kitti
  • 10. The effect of UV irradiation on gene expression - Ádám Zoltán Mihály
  • ...
  • 11. The effect of UV irradiation on gene expression - Ádám Zoltán Mihály
  • 12. The effect of UV irradiation on gene expression - Ádám Zoltán Mihály
  • 13. BLASTS - bioinformatics - Ádám Zoltán Mihály
  • 14. BLASTS - bioinformatics - Ádám Zoltán Mihály
  • 15. BLASTS - bioinformatics - Garai Kitti
  • 16. BLASTS - bioinformatics - Garai Kitti
  • 17. Designing disease models - Chromosomal modification - Downsyndrome mouse model - Garai Kitti
  • ...
  • 18. Designing disease models - Chromosomal modification - Downsyndrome mouse model - Garai Kitti
  • 19. Designing disease models - Chromosomal modification - Downsyndrome mouse model - Garai Kitti
  • 20. Designing disease models - Chromosomal modification - Downsyndrome mouse model - Garai Kitti
  • 21. Designing disease models - transposons - Garai Kitti
  • 22. Designing disease models - transposons - Garai Kitti
  • 23. Designing disease models - transposons - Ádám Zoltán Mihály
  • 24. Designing disease models - transposons - Ádám Zoltán Mihály
  • 25. Swiss prot - protein sequences in disease analysis - Ádám Zoltán Mihály
  • ...
  • 26. Swiss prot - protein sequences in disease analysis - Ádám Zoltán Mihály
  • 27. Swiss prot - protein sequences in disease analysis - Ádám Zoltán Mihály
  • 28. Swiss prot - protein sequences in disease analysis - Ádám Zoltán Mihály

Seminars

  • 3. Induced mutations induced by chemicals - Garai Kitti
  • 2. Replication errors and Base modifications - Garai Kitti
  • 1. Replication errors and Base modifications - Garai Kitti
  • 4. Induced mutations induced by radiation - Garai Kitti
  • 5. Mutations in the background of human diseases case study I. - Garai Kitti
  • 6. Mutations in the background of human diseases case study II. - Garai Kitti
  • 7. Mutations in the background of human diseases case study III. - Garai Kitti
  • 8. Comparison of gene expression regulation in bacteria and humans I. - Garai Kitti
  • 9. Comparison of gene expression regulation in bacteria and humans II. - Ádám Zoltán Mihály
  • 10. Comparison of gene expression regulation in bacteria and humans III. - Ádám Zoltán Mihály
  • 11. Comparison of gene expression regulation in bacteria and humans IV. - Ádám Zoltán Mihály
  • 12. Epigenetics in the background of human diseases case study I. - Ádám Zoltán Mihály
  • 13. Epigenetics in the background of human diseases case study II. - Ádám Zoltán Mihály
  • 14. Epigenetics in the background of human diseases case study III. - Ádám Zoltán Mihály

Reading material

Obligatory literature

Literature developed by the Department

Own ppt, interactive teaching material

Notes

Recommended literature

Klug et al: Concepts of Genetics 12th Edition

Pierce: Genetics - A Conceptual Approach 7th Edition (2020)

Conditions for acceptance of the semester

75% attendance to lectures and 85% to seminars and practices

Mid-term exams

One midterm test, that can be repeated two more times if necessary.

Making up for missed classes

None

Exam topics/questions

Teams, Neptun, Departmental website

Examiners

  • Garai Kitti
  • Pongrácz Judit Erzsébet

Instructor / tutor of practices and seminars

  • Ádám Zoltán Mihály
  • Draskóczi Lilla Gréta
  • Garai Kitti